neuroscience
the study of the nervous system, especially the brain (the brain is the seat of learning and memory)
nervous system
the system that distributes and processes information; made of two parts
central nervous system
the brain and the spinal cord
peripheral nervous system
nerve fibers that connect the CNS to the rest of the body
neurons
nerve fibers that collect and process incoming information
cerebral cortex
the brain matter found on the top and sides of the brain; made of four parts
frontal lobe
plans and performs action
occipital lobe
important for vision
parietal lobe
handles sensory information
temporal lobe
important for hearing
cerebellum
sits behind the cortex and coordinates movement
brainstem
connects the brain to the spinal cord and regulates automatic functions, like breathing
thalamus
receives sensory information and relays it to the brain
basal gangalia
involved in learning skilled movements
hippocampus
linked to learning new facts and memory
amygdala
linked to emotion
incoming stimuli sensory pathways
primary sensory cortices are first stage of cortical sensory processing; more advanced processing occurs in adjacent cortical regions
outgoing response
primary motor cortex gets input from frontal lobes, cerebellum, basal ganglia, and brainstem (brainstem-->spinal cord-->motor fibers)
human neuropsychology
studies the relationship of brain function to behavior
Karl Lashley
conducted brain lesions and found that there is not a specific engram that causes memory problems; the size of the removal is what matters
Theory of Equipotentiality
theory that says that the brain acts a whole to store memories; there is no single area
Functional neuroimaging
shows the activity or function of the living brain
fMRI
reflects local blood oxygenation; works because highly active areas use more oxygen
PET
reflects blood flow or glucose utilization; works because highly active areas use more oxygen, it require more blood flow
Electroencephalography (EEG)
electrodes on the scalp that measure roar of axons firing in brain areas form two-dimensional "brain wave"
Event-related potentials (ERPs)
an average EEGs from a repeated event that can measure changes in brain activity during learning and memory tasks
Four Basic Levels of Brain Function
1. Behavior 2. Neural System 3. Cellular/Synaptic Mechanisms 4.

Molecular Mechanisms

Observation
a method used to study learning and memory; that views behavior
Correlation
a method used to study learning and memory; that studies the cause and effect of areas/neurons with organs/behavior
Perturbation
a method used to study learning and memory; that infers function from dysfunction and hyperfunction
Mimicry (simulation)
a method used to study learning and memory; activation of effector organ or behavior by stimulating molecular entities or neurons
Synaptic plasticity
the potential for synapses to be modified
Long-Term Potentiation (LTP)
a long-lasting enhancement in signal transmission between two neurons that results from stimulating them synchronously
Hebb's postulate
cells that fire together, are wired together
associativity of LTP and learning/memory
when things are related, they are easier to recall, just how when something is activated, the adjacent cells are easier to fire.