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Decreased liver enzymes, reduced kidney function and reduced liver perfusion

Wheezing, swallowing difficulty, itching, tachycardia, angiogram facial swelling

Extended release because they release over a lengthy period of time a patients can take less often

Require use of contraception in women of childbearing age, can cause fetal malformations, can pass through the umbilical cord, weight benefits against risk

Drug toxicity

Tolerance to the drug

Do not require PCp supervision, can interact with other drugs, should be included in history, and may consist toxicity

Do not crush or chew meds, drug is supposed to reach small intestine

Periodic la. Tests, monitor for indications of toxicity, take smallest effective dose

As soon as possible

Can indicate drug hypersensitivity and allergic reaction

IV

Drug tox, max effective dose, constant therapeutic level

Cognitive level, language, comfort level, readiness to learm

Time it takes drug to demonstrate full therapeutic effect. Blood glucose is lowest at peak drug time

Check creatinine clearance which checks renal and liver function

Older kids have a higher metabolism and metabolize drugs faster

Achieve desired effect with using lower dosages, both drugs gave similar actions

Causes drug toxicity. Inhibits enzyme in liver that metabolizes drugs

Cardiac dysrythmias, non therapeutic

Delayed gastric emptying is slower in infants, which can increase absorption in the stomach but not the intestine

Fetal malformation

Decreased bioavailability because of the first pass effect

IV, subcutaneous, and IM

Newborns weight, how much child breast feeds, benefits to mom outweigh risks to baby, properties of drug

Take drug in morning, non amphetamine stimulant, taking in morning will help to improve wakefulness. Taken1 hr before work

Memory impairment

Interferon beta drugs can cause feve, chills, headaches and muscle aches. Premedication with acetaminophen or an NSAID can help minimize this

Increases dopamine in extra pyramidal center of brain

Drowsiness, sedation, rash is a side effect of anti epileptic drugs

Because of the potential for bone marrow suppression and decreased platelet count patients should report bruising bleeding or fatigue

Increased focus

Notify PCP if they start taking OTC antacids that contain sodium bicarbonate because that can decrease excretion leading to toxicity

Tachycardia

Change position slowly because it can cause orthostatic hypotension

Liver function serious adverse effect of dantrolene. Regular intervals and advise patient to report jaundice or abdominal pain

Monitor CPK creatinine phosphor insane enzyme found in the heart brain and skeletal muscle. Monitoring CPK can allow possibility of skeletal muscle damage from the drug

Centrally acting muscle relaxant. Avoid driving

Nausea vomiting and diarrhea. Taking drug with food can help

Avoid alcohol and other cns depressants, take 30 min before bedtime, taper drug slowly

Chest pain is number 1. Should report any tightness in jaw, chest, or back. Not an appropriate choice for history of coronary artery disease

Valproate acid can cause an increase in phenytoin blood levels causing toxicity

Titration from the lowest possible dosage, visual disturbances, vertigo and ataxia can occur. Dosage should be low

Causes amnesia and anti anxiety

Short acting barbiturate can cause respiratory depression. Mechanical ventilation and monitoring are essential

When systemically absorbed lidocaine can cause HYPOTENSION especially when used as a spinal anesthetic

Prolonged diarrhea can cause dehydration and is an adverse effect of dantrolene . Need to report

Jaundice abdominal pain and nausea

Muscle rigidity, stupor agitation, hypertension, and fever

apply gentle pressure to nasolacrimal duct for 1 min. Do not touch tip of dropper, remove contact lenses

Wear sunscreen, limit exposure to sunlight

Change positions slowly, do not stop taking abruptly, take at bedtime to prevent daytime drowsiness, increase fluid and fiber intake

Monitor thyroid function tests because hypothyroidism is an adverse effect, patients should report neck enlargement weight gain and lethargy

They can trigger hypertension in patients taking phenelzine. Headache nausea and lethargy

Bradycardia,can also expect some ocular stinging upon admin

Cataracts or opacity of the lens, report any changes in vision, cloudiness or halos around the eyes

Seasonal affective disorder, smoking cessation, and depression

Report suicidal thoughts

Asthmatic because a beta blocker can cause bronchospasm

Acute dystopia can develop during the first few days of treatment with Thorazine, treatment includes admin if Benadryl

Anxiety, respiratory depression, sedation and tolerance. Avoid alcohol

Avoid NSAIDS because they increase the renal absorption of lithium and sodium. Concurrent use is contraindicated

Polyurethane, can cause new-onset DM. Check glucose regularly

Lithium toxicity in the form of hypertension, LASIK increases sodium loss and can cause lithium absorption.

Can cause seizure activity when patients have a cns tumor or hx of head trauma

Allow 2 to 4 weeks to feel effects

Blood pressure... At risk for hypotension. Should remain supine for 3o min. Essential to infuse slowly

Serotonin syndrome can begin 2 to 72 hours after taking Prozac. Mental confusion, agitAtion

Imipramine tofranil.

Should not be taken together. Phenelzine is an maoi.

Provide cooling measures, discontinue anesthesia

Gentamicin, an amino glycoside, which can interact with neuromuscular blocker increasing prolonged paralysis

Make sure not allergic to fish, report rash or itching, prime the pump, report nasal, irritation

Bradycardia, measure apical pulse and notify if below 60 bpm. It is essential to have atropine on hand

Causes muscle paralysis by binding with cholinergic receptors at the neuromuscular junction. Mimics acetylcholine

Joint pain and muscle pain, nausea, visual disturbance and esophagitis

Skin rash can cause serious infection such as Steven Johnson syndrome

Keep atropine on hand

Mimics the effects of estrogen on bone tissue. Minimizing or stopping bone loss

Infection from both med and disease process

Asthma because ain't can cause bronchospasm. A monitor breath sounds and have atropine on hand

Jaw pain, blurred vision, and muscle pain

Reports flank pain which indicated renal calculi, patient should increase water intake and report blood in urine or flank Paine

Malignant hyperthermia is suspected

Decreases activity a of osteoclasts

Drink 8 oz of water with calcium tabs, chew calcium tabs before swallowing, take drugs 1hour apart, divide doses in 3 doses

Should remain flat on bed rest, patient has to sit or stand for 30 minutes to prevent esophagitis

Calf pain indicates DVTa

Shortness of breath, cough elevated BP and heart rate

Drink 2 to 3 L per day, can cause kidney damage so you need to drink a lot of water o

Avoid people who are sick, periodic lab tests, report bruising or Petechia, avoid drinking alcohol

Hyper kalmia myasthenia gravis, and respiratory depression

Tremors, confusion, nausea, muscle weakness

Can cause gastric irritation so watch for black Garry stools

Increase activity such as walking, use a contraceptive if there is any chance of pregnancy increase intake of calcium and vitamin